Using Adenosine for Pulmonary Artery Hypertension

In testing adenosine for pulmonary artery hypertension, researchers have begun to make headway in treating one of the most dangerous diseases relating to high blood pressure.

The pulmonary arterial system consists of two arteries, the long right pulmonary artery and the shorter left pulmonary artery. They act together to transmit blood to the lungs.

Pulmonary artery hypertension, also known as PAH, is a condition where there is systemic and ongoing high blood pressure in the pulmonary artery.

The incidences of pulmonary artery hypertension is not very high in the general population, but when it does occur it can possibly be fatal - especially in its most severe form. In it's lesser forms, it can still cause problems such as blocked or leaky heart valves and make it more difficult for the heart to pump blood to the lungs. Currently, there is no known cause for pulmonary artery hypertension and most experts attribute it to heredity.

To combat the problem, researchers have experimented with using Adenosine. Adenosine is a building block of DNA and a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule.

One of the really useful things that Adenosine can do is to prevent or inhibit body tissue damage. In the case of arterial hypertension, it can possibly prevent further damage from occurring in the pulmonary articles. In some animal studies, adenosine has even shown an ability to repair injured body tissue.

Ongoing trials are studying the usages of adenosine in regulating vascular tone in cases where pulmonary artery hypertension has already taken place. Of course, adenosine is not the only treatment being used to treat pulmonary hypertension, Researchers are also studying the effects of calcium channel blockers on pulmonary artery hypertension, both by itself and in combination with adenosine.

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